Lithium was first used in a trial treatment of manic behavior. On March 29, Australian John F. J. Cade gave lithium citrate to "a little wizened man of 51 who had been in a chronic state of excitement for five years. He was amiably restless, dirty, destructive, and interfering." The treatment was surprisingly effective and the patient was discharged on July 9, 1948.

Type of event: Other Notable Event

Country: Australia

Region: Oceania